General Themes
My main research interests are in diffuse optical imaging, especially medical imaging. I'm especially interested in understanding the role that scattering plays in the image formation process, and how we can build realistic models of light propagation in diffusing media. Once a model has been constructed we use it to deduce properties of the tissue from optical images. I'm especially interested in bespoke models of light propagation that include prior information about the structure and composition of the tissue. This should, in principle, constrain the inversion process that is required to deduce the tissue properties, leading to more accurate maps of the tissue that are of use in the clinical setting.
My recent research has centred on the development of a novel image analysis method to the early detection of diabetic retinopathies via simple digital photography. The technique relies on understanding the image formation process, and constructing a model which can predict the colouration of the retina based upon its histological composition. This model can then be used to solve the inverse problem of determining the histology based upon an image. Most recently, I have been looking at how we can adapt these methods for the quantification of macular pigmentation - a key indicator of the onset of age-related macular degeneration.
Publications more details
A complete list of my publications can be found on my publications page.
Grants
Current Grants
- Multispectral Retinal Image Analysis (MRIA): A new technique for the assessment of Age-related Macular Degeneration and its treatment. Funded by the Dunhill Medical Trust (with Ela Claridge (University of Birmingham, Computer Science) and Hannah Bartlett, Frank Eperjesi, Jon Gibson (Aston University, Health Sciences)).
Previous Grants
- Modular discrete-wavelength light source synchronised with an intensity imaging camera for high-speed multispectral imaging. Funded by the EPSRC under grant number EP/E065236/1 with Ela Claridge (University of Birmingham, Computer Science) and Jeremy Hebden (UCL, Medical Physics).
Collaborators
- Josephine Bunch (Birmingham, Chemistry)
- Hamid Dehghani, Ela Claridge (Birmingham, Computer Science)
- Jeremy Hebden, Nick Everdell (UCL, Medical Physics)
- Hannah Bartlett, Frank Eperjesi, Jon Gibson (Aston, Health Sciences)