Addressed-Array Approach to DNA Computation Readout through UV Photopatterning

Created by W.Langdon from gp-bibliography.bib Revision:1.4216

  author =       "S. D. Gillmor and Q. Liu and L. Wang and 
                 C. E. Jordan and A. G. Frutos and A. J. Theil and T. C. Stother and 
                 A. E. Condon and R. M. Corn and L. M. Smith and 
                 M. G. Lagally",
  title =        "Addressed-Array Approach to {DNA} Computation Readout
                 through {UV} Photopatterning",
  booktitle =    "1998 March Meeting of the American Physical Society",
  year =         "1998",
  month =        "16-20 " # mar,
  pages =        "2403-+",
  address =      "Los Angeles",
  organisation = "APS",
  keywords =     "genetic algorithms, genetic programming",
  URL =          "",
  abstract =     "Surfaced-based DNA computation allows for the
                 efficient manipulation of operations on DNA strands.
                 The readout operation determines the DNA strand
                 sequence that encodes the solution of a combinatorial
                 problem of interest; to perform it, densely addressed
                 arrays are a necessity. In our surfaced-based approach,
                 we photopattern self-assembled monolayers (SAMs)
                 attached to a gold surface creating specific regions of
                 hydrophilic islands in a hydrophobic background, and we
                 characterise the chemically modified surface through
                 reflection FTIR and fluorometry. Subsequently, the DNA
                 strands, short 31 base-pair oligonucleotides that
                 encode 4-8 bits of data, attach to the hydrophilic
                 islands and form addressed arrays with feature sizes in
                 the submillimeter range. With simple addressed arrays,
                 we can perform the readout operation for a
                 combinatorial problem. Expanding this simple technique,
                 possibly with ink jet printer technology, readout can
                 be modified to solve complex combinatorial problems
                 employing arrays of 16 by 16 or larger with features
                 sizes on the micrometer scale.",
  adsurl =       "",
  adsnote =      "Provided by the Smithsonian/NASA Astrophysics Data
  notes =        "See \cite{gillmor:1998:aaaDNAcrUVp}",

Genetic Programming entries for Susan D Gillmor Qinghua Liu Liman Wang C E Jordan Anthony G Frutos Andrew J Thiel Todd Strother Anne E Condon Robert M Corn Lloyd M Smith Max G Lagally