Application of artificial neural networks (ANNs) and genetic programming (GP) for prediction of drug release from solid lipid matrices

Created by W.Langdon from gp-bibliography.bib Revision:1.3973

@Article{Gures2012,
  author =       "Sinan Gures and Aleksander Mendyk and 
                 Renata Jachowicz and Przemyslaw Dorozynski and Peter Kleinebudde",
  title =        "Application of artificial neural networks (ANNs) and
                 genetic programming (GP) for prediction of drug release
                 from solid lipid matrices",
  journal =      "International Journal of Pharmaceutics",
  volume =       "436",
  number =       "1-2",
  pages =        "877--879",
  year =         "2012",
  ISSN =         "0378-5173",
  DOI =          "doi:10.1016/j.ijpharm.2012.05.021",
  URL =          "http://www.sciencedirect.com/science/article/pii/S0378517312005054",
  keywords =     "genetic algorithms, genetic programming, Solid lipid
                 extrusion, Artificial neural networks, Release
                 profile",
  abstract =     "The aim of the present study was to develop a
                 semi-empirical mathematical model, which is able to
                 predict the release profiles of solid lipid extrudates
                 of different dimensions. The development of the model
                 was based on the application of ANNs and GP. ANN's
                 abilities to deal with multidimensional data were
                 exploited. GP programming was used to determine the
                 constants of the model function, a modified Weibull
                 equation. Differently dimensioned extrudates consisting
                 of diprophylline, tristearin and polyethylene glycol
                 were produced by the use of a twin-screw extruder and
                 their dissolution behaviour was studied. Experimentally
                 obtained dissolution curves were compared to the
                 calculated release profiles, derived from the
                 semi-empirical mathematical model.",
}

Genetic Programming entries for Sinan Gures Aleksander Mendyk Renata Jachowicz Przemyslaw Dorozynski Peter Kleinebudde

Citations