Evolutionary algorithms and synthetic biology for directed evolution: commentary on ``on the mapping of genotype to phenotype in evolutionary algorithms'' by Peter A. Whigham, Grant Dick, and James Maclaurin

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@Article{Kell:2017:GPEM,
  author =       "Douglas B. Kell",
  title =        "Evolutionary algorithms and synthetic biology for
                 directed evolution: commentary on ``on the mapping of
                 genotype to phenotype in evolutionary algorithms'' by
                 Peter A. Whigham, Grant Dick, and James Maclaurin",
  journal =      "Genetic Programming and Evolvable Machines",
  year =         "2017",
  volume =       "18",
  number =       "3",
  pages =        "373--378",
  month =        sep,
  note =         "Special Peer Commentary on Mapping of Genotype to
                 Phenotype in Evolutionary Algorithms",
  keywords =     "genetic algorithms, genetic programming, Grammatical
                 Evolution, Directed evolution, Synthetic biology,
                 Navigating search spaces, Intelligent operators",
  ISSN =         "1389-2576",
  DOI =          "doi:10.1007/s10710-017-9292-1",
  size =         "6 page",
  abstract =     "I rehearse two issues around the commentary of Whigham
                 and colleagues. (1) There really are many more reasons
                 than those given as to why natural evolution cannot
                 reasonably find or select the optimal individual. (2) A
                 series of experimental molecular biology programmes,
                 known generically as directed evolution, can use
                 operators and selection schemes that natural evolution
                 cannot. When developed further using the methods of
                 synthetic biology, there are no operators or schemes
                 for in silico evolution that cannot be applied
                 precisely to directed evolution. The issues raised
                 apply only to natural evolution but not to directed
                 evolution.",
  notes =        "Introduction in \cite{Spector:2017:GPEM}

                 An author's reply to this comment is available at
                 http://dx.doi.org/10.1007/s10710-017-9289-9
                 \cite{Whigham:2017:GPEM2}.

                 This comment refers to the article available at:
                 http://dx.doi.org/10.1007/s10710-017-9288-x
                 \cite{Whigham:2017:GPEM}.",
}

Genetic Programming entries for Douglas B Kell

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