Classification and Screening of Recognition Protein Complexes with Genetic Programming

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@InProceedings{Kuo:2011:BIBE,
  author =       "Huang-Cheng Kuo and Jia-Hao Li",
  title =        "Classification and Screening of Recognition Protein
                 Complexes with Genetic Programming",
  booktitle =    "11th IEEE International Conference on Bioinformatics
                 and Bioengineering (BIBE 2011)",
  year =         "2011",
  month =        "24-26 " # oct,
  pages =        "287--290",
  address =      "Taichung",
  size =         "4 pages",
  abstract =     "A protein complex is either transient or obligate. In
                 the organisms, proteins recognise each other with their
                 binding sites and become transient protein complexes.
                 Proteins perform their functions through
                 protein-protein recognition. In this paper, we train a
                 model by genetic programming with physicochemical
                 properties information of the binding sites. The model
                 classifies and screens the proteins of recognition
                 interactions. The model achieves an average
                 classification accuracy of 75percent. For screening,
                 given a protein with concave binding site and a
                 database of proteins with convex binding site, from the
                 database we retrieve a small set of proteins in which
                 one of them recognises with the query protein. In
                 average, 65percent of proteins in the database are
                 screened out.",
  keywords =     "genetic algorithms, genetic programming, average
                 classification accuracy, concave binding site, convex
                 binding site, organisms, physicochemical properties,
                 protein database, protein-protein recognition, query
                 protein, transient protein complexes, biochemistry,
                 biological techniques, cellular biophysics,
                 microorganisms, molecular biophysics, physiological
                 models, proteins",
  DOI =          "doi:10.1109/BIBE.2011.51",
  notes =        "Also known as \cite{6089842}",
}

Genetic Programming entries for Huang-Cheng Kuo Jia-Hao Li

Citations