Genotype-phenotype mapping: genes as computer programs

Created by W.Langdon from gp-bibliography.bib Revision:1.4524

  author =       "Douglas B. Kell",
  title =        "Genotype-phenotype mapping: genes as computer
  journal =      "Trends in Genetics",
  year =         "2002",
  volume =       "18",
  number =       "11",
  pages =        "555--559",
  month =        nov,
  keywords =     "genetic algorithms, genetic programming",
  URL =          "",
  URL =          "",
  DOI =          "doi:10.1016/S0168-9525(02)02765-8",
  abstract =     "The effects of genes on phenotype are mediated by
                 processes that are typically unknown but whose
                 determination is desirable. The conversion from gene to
                 phenotype is not a simple function of individual genes,
                 but involves the complex interactions of many genes; it
                 is what is known as a nonlinear mapping problem. A
                 computational method called genetic programming allows
                 the representation of candidate nonlinear mappings in
                 several possible trees. To find the best model, the
                 trees are `evolved' by processes akin to mutation and
                 recombination, and the trees that more closely
                 represent the actual data are preferentially selected.
                 The result is an improved tree of rules that represent
                 the nonlinear mapping directly. In this way, the
                 encoding of cellular and higher-order activities by
                 genes is seen as directly analogous to computer
                 programs. This analogy is of utility in biological
                 genetics and in problems of genotype-phenotype
  notes =        "Opinion",

Genetic Programming entries for Douglas B Kell