Computational approaches for understanding the diagnosis and treatment of Parkinson's disease

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@Article{smith2015computational,
  author =       "Stephen L. Smith and Michael A. Lones and 
                 Matthew Bedder and Jane E. Alty and Jeremy Cosgrove and 
                 Richard J. Maguire and Mary Elizabeth Pownall and 
                 Diana Ivanoiu and Camille Lyle and Amy Cording and 
                 Christopher J. H. Elliott",
  title =        "Computational approaches for understanding the
                 diagnosis and treatment of {Parkinson's} disease",
  journal =      "IET Systems Biology",
  year =         "2015",
  volume =       "9",
  number =       "6",
  pages =        "226--233",
  keywords =     "genetic algorithms, genetic programming",
  publisher =    "IET",
  ISSN =         "1751-8849",
  DOI =          "doi:10.1049/iet-syb.2015.0030",
  abstract =     "This study describes how the application of
                 evolutionary algorithms (EAs) can be used to study
                 motor function in humans with Parkinson's disease (PD)
                 and in animal models of PD. Human data is obtained
                 using commercially available sensors via a range of
                 non-invasive procedures that follow conventional
                 clinical practice. EAs can then be used to classify
                 human data for a range of uses, including diagnosis and
                 disease monitoring. New results are presented that
                 demonstrate how EAs can also be used to classify fruit
                 flies with and without genetic mutations that cause
                 Parkinson's by using measurements of the proboscis
                 extension reflex. The case is made for a computational
                 approach that can be applied across human and animal
                 studies of PD and lays the way for evaluation of
                 existing and new drug therapies in a truly objective
                 way.",
  notes =        "PMID: 26577157

                 Dept. of Electron., Univ. of York, York, UK",
}

Genetic Programming entries for Stephen L Smith Michael A Lones Matthew Bedder Jane E Alty Jeremy Cosgrove Richard J Maguire Mary Elizabeth Pownall Diana Ivanoiu Camille Lyle Amy Cording Christopher J H Elliott

Citations